Protein kinase C mediates juvenile hormone-dependent phosphorylation of Na⁺/K⁺-ATPase to induce ovarian follicular patency for yolk protein uptake.

ABSTRACT: In oviparous animals, vitellogenesis is prerequisite to egg production and embryonic growth after oviposition. For successful insect vitellogenesis and oogenesis, vitellogenin (Vg) synthesized in the fat body (homologue to vertebrate liver and adipose tissue) must pass through the intercellular channels, a condition known as patency in the follicular epithelium, to reach the surface of oocytes. This process is controlled by juvenile hormone (JH) in many insect species, but the underlying mechanisms remain elusive. Previous work has suggested the possible involvement of Na⁺/K⁺-ATPase in patency initiation, but again, the regulatory cascade of Na⁺/K⁺-ATPase for patency initiation has been lacking. Using the migratory locust Locusta migratoria

SUBMITTER: Jing YP 

PROVIDER: S-EPMC6311519 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature