Formation of Complex α-Imino Esters via Multihetero-Cope Rearrangement of α-Keto Ester Derived Nitrones.

ABSTRACT: A sequential benzoylation and multihetero-Cope rearrangement of α-keto ester derived nitrones has been developed. The reaction furnishes a diverse array of complex α-imino ester derivatives. The products can be transformed into amino alcohols via LiAlH₄ reduction.

SUBMITTER: Bartlett SL 

PROVIDER: S-EPMC6311990 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature