Prevalence and course of lower limb disease activity and walking disability over the first 5 years of juvenile idiopathic arthritis: results from the childhood arthritis prospective study.

ABSTRACT:

Objective

The aim was to investigate the time course of lower limb disease activity and walking disability in children with JIA over a 5-year course.

Methods

The Childhood Arthritis Prospective Study is a longitudinal study of children with a new JIA diagnosis. Childhood Arthritis Prospective Study data include demographics and core outcome variables at baseline, 6 months and yearly thereafter. Prevalence and transition rates from baseline to 5 years were obtained for active and limited joint counts at the hip, knee, ankle and foot joints; and walking disability, measured using the Childhood Health Assessment Questionnaire walking subscale. Missing data were accounted for using multiple imputation.

Results

A total of 1041 children (64% female), with a median age of 7.

SUBMITTER: Hendry GJ 

PROVIDER: S-EPMC6312095 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature