Robustness of the reproductive number estimates in vector-borne disease systems.

ABSTRACT: BACKGROUND:The required efforts, feasibility and predicted success of an intervention strategy against an infectious disease are partially determined by its basic reproduction number, R0. In its simplest form R0 can be understood as the product of the infectious period, the number of infectious contacts and the per-contact transmission probability, which in the case of vector-transmitted diseases necessarily extend to the vector stages. As vectors do not usually recover from infection, they remain infectious for life, which places high significance on the vector's life expectancy. Current methods for estimating the R0 for a vector-borne disease are mostly derived from compartmental modelling frameworks assuming constant vector mortality rates. We hypothesised that some of the assumptions u

SUBMITTER: Tennant W 

PROVIDER: S-EPMC6312349 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature