Biliary tract cancer: current challenges and future prospects.

ABSTRACT:

Purpose

Incidence and mortality of biliary tract carcinoma (BTC) are increasing, especially in South America and Asia. Such a disease often bears a dismal prognosis because of diagnosis occurring at late stages and for the frequent relapses after surgery. The aims of this review were to summarize the state of the art of the treatment of BTC and give a view at possible future prospects linked with molecular profiling, immunotherapy, and targeted therapies.

Design

We conducted a systematic literature search using MEDLINE and the 2018 ASCO Meeting abstract databases to identify published clinical trials, translational series, and meeting abstracts. All significant papers and abstracts available to date were included.

Results

For resected BTC, thanks to the BILCAP study,

SUBMITTER: Ghidini M 

PROVIDER: S-EPMC6314055 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature