Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes.

ABSTRACT: Modifications in gene expression determine many of the phenotypic differentiations between closely related species. This is particularly evident in reproductive tissues, where evolution of genes is more rapid, facilitating the appearance of distinct reproductive characteristics which may lead to species isolation and phenotypic variation. Large-scale, comparative analyses of transcript expression levels have been limited until recently by lack of inter-species data mining solutions. Here, by combining expression normalisation across lineages, multivariate statistical analysis, evolutionary rate, and protein-protein interaction analysis, we investigate ortholog transcripts in the male accessory glands and testes across five closely related species in the Anopheles gambiae complex. We

SUBMITTER: Izquierdo A 

PROVIDER: S-EPMC6315087 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature