Comparative Analysis of Genomic Island Prediction Tools.

ABSTRACT: Tools for genomic island prediction use strategies for genomic comparison analysis and sequence composition analysis. The goal of comparative analysis is to identify unique regions in the genomes of related organisms, whereas sequence composition analysis evaluates and relates the composition of specific regions with other regions in the genome. The goal of this study was to qualitatively and quantitatively evaluate extant genomic island predictors. We chose tools reported to produce significant results using sequence composition prediction, comparative genomics, and hybrid genomics methods. To maintain diversity, the tools were applied to eight complete genomes of organisms with distinct characteristics and belonging to different families. Escherichia coli CFT073 was used as a cont

SUBMITTER: da Silva Filho AC 

PROVIDER: S-EPMC6315130 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature