Nonpublication Rates and Characteristics of Registered Randomized Clinical Trials in Digital Health: Cross-Sectional Analysis.

ABSTRACT:

Background

Clinical trials are key to advancing evidence-based medical research. The medical research literature has identified the impact of publication bias in clinical trials. Selective publication for positive outcomes or nonpublication of negative results could misdirect subsequent research and result in literature reviews leaning toward positive outcomes. Digital health trials face specific challenges, including a high attrition rate, usability issues, and insufficient formative research. These challenges may contribute to nonpublication of the trial results. To our knowledge, no study has thus far reported the nonpublication rates of digital health trials.

Objective

The primary research objective was to evaluate the nonpublication rate of digital health randomized cli

SUBMITTER: Al-Durra M 

PROVIDER: S-EPMC6315268 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature