Significance of Brownian Motion for Nanoparticle and Virus Capture in Nanocellulose-Based Filter Paper.

ABSTRACT: Pressure-dependent breakthrough of nanobioparticles in filtration was observed and it was related to depend on both convective forces due to flow and diffusion as a result of Brownian motion. The aim of this work was to investigate the significance of Brownian motion on nanoparticle and virus capture in a nanocellulose-based virus removal filter paper through theoretical modeling and filtration experiments. Local flow velocities in the pores of the filter paper were modeled through two different approaches (i.e., with the Hagen⁻Poiseuille equation) and by evaluating the superficial linear flow velocity through the filter. Simulations by solving the Langevin equation for 5 nm gold particles and 28 nm ΦX174 bacteriophages showed that hydrodynamic constraint is favored for larger particles. F

SUBMITTER: Gustafsson O 

PROVIDER: S-EPMC6315380 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature