Pressurized Solvent Extraction with Ethyl Acetate and Liquid Chromatography-Tandem Mass Spectrometry for the Analysis of Selected Conazole Fungicides in Matcha.

ABSTRACT: The extraction of powdered nutraceuticals is challenging due to the low water content and high concentration of matrix components that can lead to significant matrix effects in liquid chromatography-positive ion electrospray ionization-tandem mass spectrometry (LC-ESI⁺-MS/MS). In this study we assess the feasibility of using pressurized solvent extraction with ethyl acetate to reduce the co-extraction of polar matrix components. Pigment attributed to chlorophyll was removed with in-cell clean-up utilizing Anasorb 747, Florisil®, and C18. Visible inspection of the extracts showed that pigment was removed from matcha, a powdered green tea sample. Pressurized solvent extraction with in-cell clean-up can be utilized to remove pigments from powdered samples such as nutraceuticals. Average matri

SUBMITTER: Raina-Fulton R 

PROVIDER: S-EPMC6315461 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature