Development of Microfluidic Stretch System for Studying Recovery of Damaged Skeletal Muscle Cells.

ABSTRACT: The skeletal muscle occupies about 40% mass of the human body and plays a significant role in the skeletal movement control. Skeletal muscle injury also occurs often and causes pain, discomfort, and functional impairment in daily living. Clinically, most studies observed the recovery phenomenon of muscle by massage or electrical stimulation, but there are limitations on quantitatively analyzing the effects on recovery. Although additional efforts have been made within in vitro biochemical research, some questions still remain for effects of the different cell microenvironment for recovery. To overcome these limitations, we have developed a microfluidic system to investigate appropriate conditions for repairing skeletal muscle injury. First, the muscle cells were cultured in the microfluidi

SUBMITTER: Kim W 

PROVIDER: S-EPMC6315523 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature