Hyaluronate-Functionalized Graphene for Label-Free Electrochemical Cytosensing.

ABSTRACT: Electrochemical sensors for early tumor cell detection are currently an important area of research, as this special region directly improves the efficiency of cancer treatment. Functional graphene is a promising alternative for selective recognition and capture of target cancer cells. In our work, an effective cytosensor of hyaluronate-functionalized graphene (HG) was prepared through chemical reduction of graphene oxide. The as-prepared HG nanostructures were characterized with Fourier transform infrared spectroscopy and transmission electron microscopy coupled with cyclic voltammograms and electrochemical impedance spectroscopy, respectively. The self-assembly of HG with ethylene diamine, followed by sodium hyaluronate, enabled the fabrication of a label-free electrochemical impedance sp

SUBMITTER: Jing A 

PROVIDER: S-EPMC6315524 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature