PEDOT Coated Thick Film Electrodes for In Situ Detection of Cell Adhesion in Cell Cultures.

ABSTRACT: Low temperature cofired ceramics (LTCC) provide a technology for the 3-dimensional integration of sensor arrays into bioreactors covering dimensions of several hundred micrometers. Since optical control in such assemblies is not possible, the in situ detection of cell adhesion on impedance electrodes with high spatial resolution would deliver crucial information. A current limitation is the increasing impedance of microelectrodes with decreasing diameter. This study evaluates the suitability of thick film gold electrodes, pristine and coated with electropolymerized poly(3,4-ethylenedioxythiophene) (PEDOT), for the detection of cell adhesion on the electrode surface. The impedance as criterion for cell attachment is measured with a recording system for electroactive cells with the aim of im

SUBMITTER: Bartsch H 

PROVIDER: S-EPMC6315667 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature