Viscous Fingering of Miscible Liquids in Porous and Swellable Media for Rapid Diagnostic Tests.

ABSTRACT: In lateral flow and colorimetric test strip diagnostics, the effects of capillary action and diffusion on speed and sensitivity have been well studied. However, another form of fluid motion can be generated due to stresses and instabilities generated in pores when two miscible liquids with different densities and viscosities come into contact. This study explored how a swellable test pad can be deployed for measuring urea in saliva by partially prefilling the pad with a miscible solution of greater viscosity and density. The resultant Korteweg stresses and viscous fingering patterns were analyzed using solutions with added food color through video analysis and image processing. Image analysis was simplified using the saturation channel after converting RGB image sequences to HSB. The kinet

SUBMITTER: Clingan H 

PROVIDER: S-EPMC6315716 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature