Transcriptomic Characterization of the South American Freshwater Stingray Potamotrygon motoro Venom Apparatus.

ABSTRACT: Venomous animals are found through a wide taxonomic range including cartilaginous fish such as the freshwater stingray Potamotrygon motoro occurring in South America, which can injure people and cause venom-related symptoms. Ensuring the efficacy of drug development to treat stingray injuries can be assisted by the knowledge of the venom composition. Here we performed a detailed transcriptomic characterization of the venom gland of the South American freshwater stingray Potamotrygon motoro. The transcripts retrieved showed 418 hits to venom components (comparably to 426 and 396 hits in other two Potamotrygon species), with high expression levels of hyaluronidase, cystatin and calglandulin along with hits uniquely found in P. motoro such as DELTA-alicitoxin-Pse1b

SUBMITTER: Silva F 

PROVIDER: S-EPMC6315956 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature