The Genetic Diagnosis of Neurodegenerative Diseases and Therapeutic Perspectives.

ABSTRACT: Genetics has led to a new focus regarding approaches to the most prevalent diseases today. Ascertaining the molecular secrets of neurodegenerative diseases will lead to developing drugs that will change natural history, thereby affecting the quality of life and mortality of patients. The sequencing of candidate genes in patients suffering neurodegenerative pathologies is faster, more accurate, and has a lower cost, thereby enabling algorithms to be proposed regarding the risk of neurodegeneration onset in healthy persons including the year of onset and neurodegeneration severity. Next generation sequencing has resulted in an explosion of articles regarding the diagnosis of neurodegenerative diseases involving exome sequencing or sequencing a whole gene for correlating phenotypical expressi

SUBMITTER: Garcia JC 

PROVIDER: S-EPMC6316116 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature