Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices.

ABSTRACT: We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl₂ infused gelatine slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

SUBMITTER: Stumberger G 

PROVIDER: S-EPMC6316925 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature