Quantity and Reporting Quality of Kidney Research.

ABSTRACT:

Background

In 2004, researchers reported that the number of nephrology clinical trials was low and that the reporting quality of such trials was suboptimal. Furthermore, the number or quality of preclinical kidney-related studies has not been systematically evaluated.

Methods

We performed a systematic review of randomized clinical trials published in 1966-2017 (listed in the Cochrane Library) and preclinical studies published in 1945-2017 (listed in PubMed). For reporting quality analysis, we evaluated the final main paper of 118 clinical trial reports and 135 preclinical studies published in leading journals in 1996, 2006, and 2016 on the basis of criteria from the widely used CONSORT and ARRIVE guidelines.

Results

The annual number of reports of clinical kidney-rela

SUBMITTER: Chatzimanouil MKT 

PROVIDER: S-EPMC6317598 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature