Conserved and divergent development of brainstem vestibular and auditory nuclei.

ABSTRACT: Vestibular function was established early in vertebrates and has remained, for the most part, unchanged. In contrast, each group of tetrapods underwent independent evolutionary processes to solve the problem of hearing on land, resulting in a remarkable mixture of conserved, divergent and convergent features that define extant auditory systems. The vestibuloacoustic nuclei of the hindbrain develop from a highly conserved ground plan and provide an ideal framework on which to address the participation of developmental processes to the evolution of neuronal circuits. We employed an electroporation strategy to unravel the contribution of two dorsoventral and four axial lineages to the development of the chick hindbrain vestibular and auditory nuclei. We compare the chick developmental map wit

SUBMITTER: Lipovsek M 

PROVIDER: S-EPMC6317910 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature