The Association of Adiponectin and Visceral Fat with Insulin Resistance and β-Cell Dysfunction.

ABSTRACT:

Background

Obesity is a risk factor for metabolic abnormalities. We investigated the relationship of adiponectin levels and visceral adiposity with insulin resistance and β-cell dysfunction.

Methods

This cross-sectional study enrolled 1,347 participants (501 men and 846 women aged 30-64 years) at the Cardiovascular and Metabolic Diseases Etiology Research Center. Serum adiponectin levels and visceral fat were measured using enzyme-linked immunosorbent assay kits and dual-energy X-ray absorptiometry, respectively. Insulin resistance was evaluated using the homeostatic model assessment of insulin resistance (HOMA-IR) and Matsuda insulin sensitivity index. β-cell dysfunction was evaluated using the homeostatic model assessment of β-cell function (HOMA-β), insulinogenic index, a

SUBMITTER: Moon HU 

PROVIDER: S-EPMC6318440 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature