New Insights in Bladder Cancer Diagnosis: Urinary miRNAs and Proteins.

ABSTRACT: Bladder cancer is the 10th-most common cancer worldwide. The diagnosis and follow-up of patients require costly invasive methods and due to these expenses, bladder cancer continues to be one of the expensive malignancies. Early diagnosis is crucial in bladder cancer as it is in other cancers; therefore, non-invasive biomarkers for early diagnosis are very important. In this review, we aimed to focus on the most recent investigations on potential urinary micro RNA (miRNA) and protein biomarkers for bladder cancer diagnosis and their associated pathways. Studies performed by different groups were compiled and the biomarker properties of various proteins and miRNAs in the urine of bladder cancer patients were evaluated. Key studies were obtained by searching keywords "bladder cancer, urinary

SUBMITTER: Amuran GG 

PROVIDER: S-EPMC6318758 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature