Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni-infected mice.

ABSTRACT:

Background

Considerable morbidity, mortality, and economic loss result from schistosomiasis infection. Deposition of Schistosoma eggs in the hepatic portal vein is considered as the main causative agent for the development of liver fibrosis and subsequent liver cirrhosis. Probiotics are exogenous and beneficial microorganisms to living hosts against the harmful effect of many parasites. Strong evidence suggests the importance of probiotics in the control strategy of helminth. The ultimate goal of this study is to evaluate the protective effect of probiotics and yogurt on Schistosoma mansoni-induced oxidative stress and hepatic fibrosis in mice.

Methods

Mice were infected by tail immersion of schistosomal cercariae followed by an oral treatment with either probiotics or yogur

SUBMITTER: El-Khadragy MF 

PROVIDER: S-EPMC6318950 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature