A phase II randomized controlled trial of three exercise delivery methods in men with prostate cancer on androgen deprivation therapy.

ABSTRACT:

Background

Existing evidence demonstrates that 1:1 personal training (PT) improves many adverse effects of androgen deprivation therapy (ADT). Whether less resource-intensive exercise delivery models are as effective remains to be established. We determined the feasibility of conducting a multi-center non-inferiority randomized controlled trial comparing PT with supervised group (GROUP) and home-based (HOME) exercise programs, and obtained preliminary efficacy estimates for GROUP and HOME compared to PT on quality of life (QOL) and physical fitness.

Methods

Men with prostate cancer on ADT were recruited from one of two experienced Canadian centres and randomized 1:1:1 to PT, GROUP, or HOME. Randomization was stratified by length of ADT use and site. Participants completed mo

SUBMITTER: Alibhai SMH 

PROVIDER: S-EPMC6318980 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature