The long-term impact of very preterm birth on adult bone mineral density.

ABSTRACT:

Introduction

Preterm infants are at increased risk of osteopenia of prematurity due to insufficient bone mineral accretion. Data on long term effects of prematurity on bone health are conflicting. This study aimed to compare bone mineral density (BMD) in young adults born very preterm and full-term controls and to examine factors associated with long-term bone health.

Methods

This observational cross-sectional study enrolled 101 young adults (18-29 years) born <29 weeks of gestation and 95 sex- and age-matched full-term controls. Participants underwent dual-energy X-ray absorptiometry to measure areal BMD and body composition. Generalized estimated equations were used to compare groups adjusting for height Z-score, lean body mass and fat mass.

Results

Adults bo

SUBMITTER: Xie LF 

PROVIDER: S-EPMC6319299 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature