Neural predictors of 12-month weight loss outcomes following bariatric surgery.

ABSTRACT:

Background/objectives

Despite the effectiveness of bariatric surgery, there is still substantial variability in long-term weight outcomes and few factors with predictive power to explain this variability. Neuroimaging may provide a novel biomarker with utility beyond other commonly used variables in bariatric surgery trials to improve prediction of long-term weight-loss outcomes. The purpose of this study was to evaluate the effects of sleeve gastrectomy (SG) on reward and cognitive control circuitry postsurgery and determine the extent to which baseline brain activity predicts weight loss at 12-month postsurgery.

Subjects/methods

Using a longitudinal design, behavioral, hormone and neuroimaging data (during a desire for palatable food regulation paradigm) were collected fro

SUBMITTER: Holsen LM 

PROVIDER: S-EPMC6319374 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature