Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

ABSTRACT: Upper airway stimulation (UAS) has been shown to reduce severity of obstructive sleep apnoea. The aim of this study was to identify predictors of UAS therapy response in an international multicentre registry.Patients who underwent UAS implantation in the United States and Germany were enrolled in an observational registry. Data collected included patient characteristics, apnoea/hypopnoea index (AHI), Epworth sleepiness scale (ESS), objective adherence, adverse events and patient satisfaction measures. Post hoc univariate and multiple logistic regression were performed to evaluate factors associated with treatment success.Between October 2016 and January 2018, 508 participants were enrolled from 14 centres. Median AHI was reduced from 34 to 7 events·h^-1, median ESS reduced

SUBMITTER: Heiser C 

PROVIDER: S-EPMC6319796 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature