HFIP-Promoted Bischler Indole Synthesis under Microwave Irradiation.

ABSTRACT: 1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP) was found to be effective for the Bischler indole synthesis under microwave irradiation in the absence of a metal catalyst. Under the catalysis of HFIP, a wide range of α-amino arylacetones were successfully transformed into indole derivatives with moderate to good yields.

SUBMITTER: Yao G 

PROVIDER: S-EPMC6321335 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature