Ontology highlight
ABSTRACT:
SUBMITTER: Blocher R
PROVIDER: S-EPMC6321446 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Blöcher René R Rodarte Ramírez Ariel A Castro-Escarpulli Graciela G Curiel-Quesada Everardo E Reyes-Arellano Alicia A
Molecules (Basel, Switzerland) 20181124 12
With the increasing antibiotic resistance of bacterial strains, alternative methods for infection control are in high demand. <i>Quorum sensing</i> (QS) is the bacterial communication system based on small molecules. QS is enables bacterial biofilm formation and pathogenic development. The interruption of QS has become a target for drug discovery, but remains in the early experimental phase. In this study, we synthesized a set of six compounds based on a scaffold (alkyl-quinoxalin-2(1<i>H</i>)-o ...[more]