Gout and the risk of Parkinson's disease in older adults: a study of U.S. Medicare data.

ABSTRACT:

Background

In the presence of limited available data, our objective was to assess the association of gout with the risk of incident Parkinson's disease (PD) in adults 65 years or older.

Methods

We used the 5% random sample of Medicare claims data from 2006 to 2012 to examine the association of gout with incident PD. The multivariable Cox regression model adjusted for demographics, comorbidity, and common cardiovascular disease and gout medications. We calculated hazard ratios (HR) and 95% confidence interval (CI). Sensitivity analyses adjusted for comorbidity categorically, or individually and for additional cardiovascular comorbidities.

Results

In a cohort study, 1.72 million Medicare beneficiaries were eligible. The mean age was 75 years (standard deviation [SD], 7.

SUBMITTER: Singh JA 

PROVIDER: S-EPMC6321725 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature