Association between Inhaled Corticosteroid Use and Pulmonary Nontuberculous Mycobacterial Infection.

ABSTRACT:

Rationale

Nontuberculous mycobacterial (NTM) pulmonary disease prevalence is increasing.

Objectives

To determine the association between the use of inhaled corticosteroids and the likelihood of NTM pulmonary infection among individuals with treated airway disease.

Methods

We conducted a case-control study of subjects with airway disease with and without NTM pulmonary infection (based on mycobacterial respiratory cultures) between 2000 and 2010 in northern California. We quantified the use of inhaled corticosteroids, other airway disease medications, and healthcare use within 6 months of NTM pulmonary infection identification. We used 1:10 case-control matching and conditional logistic regression to evaluate the association between the duration and cumulative dosage of

SUBMITTER: Liu VX 

PROVIDER: S-EPMC6321990 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature