Restrictive Spirometry Pattern, Cardiac Structure and Function, and Incident Heart Failure in African Americans. The Jackson Heart Study.

ABSTRACT:

Rationale

Although chronic obstructive pulmonary disease has been related to heart failure, the relationship between the restrictive spirometry pattern (forced vital capacity [FVC] < 80% predicted with preserved forced expiratory volume in 1 second [FEV₁]/FVC ratio) and heart failure is poorly understood.

Objectives

To determine whether having a restrictive spirometry pattern is associated with incident heart failure hospitalization.

Methods

Community-dwelling African Americans from the Jackson Heart Study (total n = 5,306; analyzed n = 4,210 with spirometry and heart failure outcome data) were grouped by restrictive spirometry (FEV₁/FVC ≥ 0.70, FVC < 80%; n = 840), airflow obstruction (FEV₁/FVC < 0.70; n = 341), and normal spirometry

SUBMITTER: Jankowich M 

PROVIDER: S-EPMC6321994 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature