Hospital Volume of Immunosuppressed Patients with Sepsis and Sepsis Mortality.

ABSTRACT:

Rationale

Immunosuppressive medical conditions are risk factors for mortality from severe infections. It is unknown whether hospital characteristics affect this risk.

Objectives

To determine whether the odds of death for an immunosuppressed patient with sepsis relative to a nonimmunosuppressed patient with sepsis varies according to the hospital's yearly case volume of immunosuppressed patients with sepsis.

Methods

Patients with sepsis at hospitals in the Vizient database were characterized as immunosuppressed or not immunosuppressed on the basis of diagnosis codes and medication use. Hospitals were grouped into quartiles based on their average volumes of immunosuppressed patients with sepsis per year. Multilevel logistic regression with clustering of patients by hosp

SUBMITTER: Greenberg JA 

PROVIDER: S-EPMC6322036 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature