Bacterial community structure and effects of picornavirus infection on the anterior nares microbiome in early childhood.

ABSTRACT:

Background

Little is known regarding the nasal microbiome in early childhood and the impact of respiratory infection on the infants' nasal microbial composition. Here we investigated the temporal dynamics and diversity of the bacterial composition in the anterior nares in children attending daycare centers.

Results

For our investigation, we considered 76 parental-taken nasal swabs of 26 children (aged 13 to 36 months) collected over a study period of 3 months. Overall, there was no significant age-specific effect or seasonal shift in the nasal bacterial community structure. In a sub-sample of 14 healthy children the relative abundance of individual taxa as well as the overall diversity did not reveal relevant changes, indicating a stable community structure over the entire s

SUBMITTER: Caputo M 

PROVIDER: S-EPMC6322332 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature