Relation of cigarette smoking and alcohol drinking in midlife with risk of cognitive impairment in late life: the Singapore Chinese Health Study.

ABSTRACT:

Background

the relations of cigarette smoking and alcohol drinking with risk of cognitive impairment remain inconsistent.

Methods

to examine the independent and joint relations of smoking and alcohol drinking with cognitive impairment, we used data from 16,948 men and women, who had been followed-up for 16-23 (mean of 20) years as participants of the Singapore Chinese Health Study, a population-based prospective cohort. Data on smoking and alcohol drinking were collected at baseline (1993-98), when participants were aged 45-74 (mean 53) years. Cognition was assessed using a 30-item Mini-Mental State Examination during follow-up three visits (2014-16), when participants were aged 61-96 (mean 73) years. Multivariable logistic regression models were used to estimate the odd rat

SUBMITTER: Wu J 

PROVIDER: S-EPMC6322505 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature