Profiling of advanced glycation end products uncovers abiotic stress-specific target proteins in Arabidopsis.

ABSTRACT: Non-enzymatic post-translational modifications of proteins can occur when the nucleophilic amino acid side chains of lysine and arginine encounter a reactive metabolite to form advanced glycation end products (AGEs). Glycation arises predominantly from the degradation of reducing sugars, and glycation has been observed during metabolic stress from glucose metabolism in both animals and plants. The implications of glycating proteins on plant proteins and biology has received little attention, and here we describe a robust assessment of global glycation profiles. We identified 112 glycated proteins that were common under a range of growth conditions and abiotic stress treatments, but also showed rosette age, diurnal, and drought stress-specific targets. Among 18 drought stress-specific glyca

SUBMITTER: Chaplin AK 

PROVIDER: S-EPMC6322573 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature