Higher intraoperative plasma transfusion volumes are associated with inferior perioperative outcomes.

ABSTRACT:

Background

Intraoperative plasma transfusion is common, yet little is known regarding its effects on perioperative coagulation tests or clinical outcomes.

Study design and methods

This is a retrospective cohort study of adults receiving intraoperative plasma transfusion at a single center from 2011 to 2015. Relationships between plasma transfusion volume, changes in coagulation test values, and clinical outcomes, including a primary outcome of early postoperative red blood cell (RBC) transfusion, were assessed with multivariable regression analyses. Secondary outcomes included hospital mortality, intensive care unit (ICU)- and hospital-free days, intraoperative RBC transfusions, and estimated blood loss.

Results

A total of 3393 unique patients were included, with medi

SUBMITTER: Warner MA 

PROVIDER: S-EPMC6322936 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature