Alcohol drinking patterns and liver cirrhosis risk: analysis of the prospective UK Million Women Study.

ABSTRACT:

Background

Alcohol is a known cause of cirrhosis, but it is unclear if the associated risk varies by whether alcohol is drunk with meals, or by the frequency or type of alcohol consumed. Here we aim to investigate the associations between alcohol consumption with meals, daily frequency of consumption, and liver cirrhosis.

Methods

The Million Women Study is a prospective study that includes one in every four UK women born between 1935 and 1950, recruited between 1996 and 2001. In 2001 (IQR 2000-03), the participants reported their alcohol intake, whether consumption was usually with meals, and number of days per week it was consumed. Cox regression analysis yielded adjusted relative risks (RRs) for incident cirrhosis, identified by follow-up through electronic linkage to rout

SUBMITTER: Simpson RF 

PROVIDER: S-EPMC6323353 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature