Relationship of Circulating Fetuin-A Levels with Body Size and Metabolic Phenotypes.

ABSTRACT:

Background

Previous studies have suggested the existence of distinct body size subgroups according to metabolic health referred to as metabolically healthy obesity (MHO) and metabolically abnormal but normal weight (MANW) patients. Although nonalcoholic fatty liver disease (NAFLD) is strongly associated with obesity and metabolic syndrome, the relationship between these phenotypes and fetuin-A, a representative hepatokine, has not been explored.

Methods

We examined the association between circulating fetuin-A levels, metabolic health phenotypes, cardiometabolic risk parameters, and subclinical atherosclerosis in 290 subjects who were randomly selected from an ongoing cohort study.

Results

Fetuin-A concentrations were significantly associated with detrimental anthropom

SUBMITTER: Chung HS 

PROVIDER: S-EPMC6323440 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature