Vanadyl Sulfate Effects on Systemic Profiles of Metabolic Syndrome in Old Rats with Fructose-Induced Obesity.

ABSTRACT:

Background

Currently, energy obtained from hypercaloric diets has been part of the obesity and type 2 diabetes mellitus (T2DM) epidemics from childhood to old age. Treatment alternatives have been sought from plants, minerals, and trace elements with metabolic effects. Vanadyl sulfate (VS) has been investigated as a hypoglycemic compound in animal and human studies showing effective insulin-mimetic properties. This characteristic encompasses several molecules that have beneficial pleiotropic effects. The aim was to determine the antiobesity, hypoglycemic, and hypolipidemic effects of VS on fructose-induced metabolic syndrome in aged rats.

Material and methods

Five groups of male Wistar rats were made, each with six rats: two groups with normal diet (ND) and three with

SUBMITTER: Ortega-Pacheco D 

PROVIDER: S-EPMC6323508 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature