CoevDB: a database of intramolecular coevolution among protein-coding genes of the bony vertebrates.

ABSTRACT: The study of molecular coevolution, due to its potential to identify gene regions under functional or structural constraints, has recently been subject to numerous scientific inquiries. Particular efforts have been conducted to develop methods predicting the presence of coevolution in molecular sequences. Among these methods, a few aim to model the underlying evolutionary process of coevolution, which enable to differentiate the shared history of genes to coevolution and thus improve their accuracy. However, the usage of such methods remains sparse due to their expensive computational cost and the lack of resources alleviating this issue. Here we present CoevDB (http://phylodb.unil.ch/CoevDB), a database containing the result of a large-scale analysis of intramolecular coevolution of 8201

SUBMITTER: Meyer X 

PROVIDER: S-EPMC6324051 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature