Feasibility of Coronary ¹⁸F-Sodium Fluoride Positron-Emission Tomography Assessment With the Utilization of Previously Acquired Computed Tomography Angiography.

ABSTRACT:

Background

We assessed the feasibility of utilizing previously acquired computed tomography angiography (CTA) with subsequent positron-emission tomography (PET)-only scan for the quantitative evaluation of ¹⁸F-NaF PET coronary uptake.

Methods and results

Forty-five patients (age 67.1±6.9 years; 76% males) underwent CTA (CTA1) and combined ¹⁸F-NaF PET/CTA (CTA2) imaging within 14 [10, 21] days. We fused CTA1 from visit 1 with ¹⁸F-NaF PET (PET) from visit 2 and compared visual pattern of activity, maximal standard uptake (SUVmax) values, and target to background ratio (TBR) measurements on (PET/CTA1) fused versus hybrid (PET/CTA2). On PET/CTA2, 226 coronary plaques were identified. Fifty-eight coronary segments from 28 (62%) patients had high <

SUBMITTER: Kwiecinski J 

PROVIDER: S-EPMC6324180 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature