Rotavirus Gastroenteritis Infection Among Children Vaccinated and Unvaccinated With Rotavirus Vaccine in Southern China: A Population-Based Assessment.

ABSTRACT:

Importance

Since 2000, the Lanzhou lamb rotavirus vaccine has been exclusively licensed in China for voluntary rotavirus gastroenteritis (RV-GE) prevention.

Objective

To evaluate the association of the Lanzhou lamb rotavirus vaccination with RV-GE among children in southern China.

Design, setting, and participants

This cross-sectional, ecological study was set in Guangzhou, China. Participants were infants possibly vaccinated (aged 2 months to 3 years) and the children ineligible for vaccination (aged ≥4 years). The study was conducted from May 1, 2007, to April 30, 2016, and the data analysis was conducted in July 2016.

Main outcomes and measures

Annual median age at onset of RV-GE and seasonal distribution of incidence. Cases of RV-GE in Guangzhou, China, dia

SUBMITTER: Fu C 

PROVIDER: S-EPMC6324266 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature