Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer.

ABSTRACT:

Importance

Stereotactic ablative radiotherapy (SABR) is first-line treatment for patients with early-stage non-small cell lung cancer (NSCLC) who cannot undergo surgery. However, up to 1 in 6 such patients will develop isolated local recurrence (iLR) or isolated regional recurrence (iRR). Little is known about outcomes when disease recurs after SABR, or about optimal management strategies for such recurrences.

Objective

To characterize long-term outcomes for patients with iLR or iRR after SABR for early-stage NSCLC with the aim of informing treatment decision making for these patients with potentially curable disease.

Design, setting, and participants

In this cohort study, a retrospective review was conducted of 912 patients prospectively enrolled in an institutional

SUBMITTER: Brooks ED 

PROVIDER: S-EPMC6324276 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature