Assessment of Risk Factors and Biomarkers Associated With Risk of Cardiovascular Disease Among Women Consuming a Mediterranean Diet.

ABSTRACT:

Importance

Higher Mediterranean diet (MED) intake has been associated with lower risk of cardiovascular disease (CVD), but limited data are available about the underlying molecular mechanisms of this inverse disease association in human populations.

Objective

To better characterize the relative contribution of traditional and novel factors to the MED-related risk reduction in CVD events in a US population.

Design, setting, and participants

Using a prospective cohort design, baseline MED intake was assessed in 25 994 initially healthy US women in the Women's Health Study who were followed up to 12 years. Potential mediating effects of a panel of 40 biomarkers were evaluated, including lipids, lipoproteins, apolipoproteins, inflammation, glucose metabolism and insulin r

SUBMITTER: Ahmad S 

PROVIDER: S-EPMC6324327 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature