Evaluation of Differences in Temporal Synchrony Between Brain Regions in Individuals With Autism and Typical Development.

ABSTRACT:

Importance

Despite reports of widespread but heterogeneous atypicality of functional connectivity in individuals with autism, little is known regarding the temporal dynamics of functional brain connections and how they relate to autistic traits.

Objective

To investigate differences in temporal synchrony between brain regions in individuals with autism and those with typical development.

Design, setting, and participants

This cohort study, conducted at the University of Utah, included 90 adolescent and adult male participants. A larger sample from the multisite Autism Brain Imaging Data Exchange (ABIDE) was also used as a replication sample. The study includes data acquired between December 2016 and April 2018. Aggregate data included in the replication sample were rel

SUBMITTER: King JB 

PROVIDER: S-EPMC6324391 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature