Assessment of Patient Medication Adherence, Medical Record Accuracy, and Medication Blood Concentrations for Prescription and Over-the-Counter Medications.

ABSTRACT:

Importance

Inaccurate medication records and poor medication adherence result in incomplete knowledge of therapy for patients.

Objective

To study accuracy of medical records and patient adherence by measuring blood concentrations of medications.

Design, setting, and participants

This cross-sectional study validated a serum-based liquid chromatography-tandem mass spectrometry assay to simultaneously quantify 263 medications used for acute and chronic conditions. The assay panel was applied to 3 clinical patient cohorts: residual serum from 1000 randomly selected samples sent for routine clinical chemistry testing between April 8 and October 6, 2015 (residuals cohort), 50 prospectively enrolled patients in a gastroenterology clinic between March 1 and March 15, 2016, wh

SUBMITTER: Sutherland JJ 

PROVIDER: S-EPMC6324396 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature