Risk of Thyroxine-Treated Autoimmune Thyroid Disease Associated With Disease Onset in Patients With Rheumatoid Arthritis.

ABSTRACT:

Importance

Autoimmune thyroid disease ([AITD] including hypothyroidism and hyperthyroidism) is the most common organ-specific autoimmune disorder and is more prevalent among patients with rheumatoid arthritis (RA). Real-world studies on when and how this increased risk of AITD develops, in association with the time before or after the onset of RA, are lacking.

Objective

To estimate the risk of thyroxine-treated AITD among patients with RA at different time points before and after the diagnosis of RA.

Design, setting, and participants

A nationwide register-based case-control and cohort study was conducted between January 1, 2006, and June 30, 2013, with a maximum follow-up time of 7 years before and 8 years after diagnosis of RA. The study used the Swedish Rheumatology

SUBMITTER: Waldenlind K 

PROVIDER: S-EPMC6324433 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature