Association of Sustained Response Duration With Survival After Conventional Transarterial Chemoembolization in Patients With Hepatocellular Carcinoma.

ABSTRACT:

Importance

Defining early reliable surrogate end points for survival in patients with hepatocellular carcinoma (HCC) after conventional transarterial chemoembolization (cTACE) is of great value.

Objective

To evaluate the association between sustained response duration (SRD) and overall survival (OS) after cTACE for intermediate HCC.

Design, setting, and participants

This multicenter cohort study enrolled 2403 consecutive patients in China with naive intermediate HCC between June 1, 2000, and December 31, 2008, as the primary cohort, and 331 consecutive patients with intermediate naive HCC between January 1, 2011, to June 30, 2012, as the validation cohort. All patients received cTACE as an initial treatment. Initial response and best response were defined as the radio

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6324454 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature