Development and Validation of a Nomogram for Assessing Survival in Patients With Metastatic Lung Cancer Referred for Radiotherapy for Bone Metastases.

ABSTRACT:

Importance

A survival prediction model for patients with bone metastases arising from lung cancer would be highly valuable.

Objective

To develop and validate a nomogram for assessing the survival probability of patients with metastatic lung cancer receiving radiotherapy for osseous metastases.

Design, setting, participants

In this prognostic study, the putative prognostic indicators for constructing the nomogram were identified using multivariable Cox regression analysis with backward elimination and model selection based on the Akaike information criterion. The nomogram was subjected to internal (bootstrap) and external validation; its calibration and discriminative ability were evaluated with calibration plots and the Uno C statistic, respectively. The training and

SUBMITTER: Yap WK 

PROVIDER: S-EPMC6324455 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature