Association of Neural Responses to Drug Cues With Subsequent Relapse to Stimulant Use.

ABSTRACT:

Importance

Although chronic relapse is a characteristic of addiction to stimulants, conventional measures (eg, clinical, demographic, and self-report) do not robustly identify which individuals are most vulnerable to relapse.

Objectives

To test whether drug cues are associated with increased mesolimbic neural activity in patients undergoing treatment for stimulant use disorder and whether this activity is associated with risk for subsequent relapse.

Design, setting, and participants

This prospective cohort study of 76 participants included a control group for baseline group comparisons. Veteran patients (n = 36) with stimulant use disorders were recruited from a 28-day residential treatment program at the Veterans Affairs Palo Alto Health Care System. Healthy controls

SUBMITTER: MacNiven KH 

PROVIDER: S-EPMC6324538 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature